From the Hunter College Biology Department:
Dr. Maria Figueiredo-Pereira, CTBR member and biology professor, will be speaking on the subject of ubiquitin-proteasome pathways at the Annual Meeting for the Society for Neuroscience. The title of the symposium is The Latest on the Ubiquitin Pathway and Central Nervous System Disease. This symposium brings together leaders in ubiquitin pathway research applied to translational medicine and drug discovery in neuroscience. The ubiquitin pathway, which governs the half-life, activity, and cell localization of most proteins, has emerged as an important means of controlling both normal brain function and dysregulated function manifested in disorders such as Alzheimer’s disease, Parkinson’s disease, polyQ disease, synaptic impairment, and neuroinflammation. Researchers who have defined these roles for ubiquitin will evaluate them in terms of their therapeutic potential in neuronal disease.