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Unconventional Roles of Ethanol Metabolizing Enzymes, Metabolites, and Cofactors in Health and Disease (R01)

Key Dates: 
  • Posted Date: December 8, 2014
  • Open Date (Earliest Submission Date): January 5, 2015
  • Letter of Intent Due Date(s): Not Applicable
  • Application Due Date(s): Standard dates apply, by 5:00 PM local time of applicant organization. All types of non-AIDS applications allowed for this funding opportunity announcement are due on these dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.
  • AIDS Application Due Date(s): Standard AIDs dates apply, by 5:00 PM local time of applicant organization. All types of types of AIDS and AIDS-related applications allowed for this funding opportunity announcement are due on these dates. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.
  • Scientific Merit Review: Standard dates apply
  • Advisory Council Review: Standard dates apply
  • Earliest Start Date: Standard dates apply
Purpose: 

The purpose of this FOA is to provide support for integrated, innovative research on the novel and unconventional contributions of ethanol metabolizing pathways, their metabolites, cofactors, and interactions with synergizing biological pathways in the development of alcohol- induced diseases and end organ injuries. It is anticipated that research supported under this FOA will generate data that leads to breakthroughs in identification and understanding of key cellular and molecular components in the initiation, progression and maintenance of the diverse medical disorders caused by excessive or long term alcohol consumption. This knowledge is critical for the diagnosis, treatment and management of vulnerable patient populations debilitated by the vast array of alcohol-induced pathologies and will enable clinicians to improve disease outcomes and, consequently, public health.

Expiration Date: 
Monday, January 8, 2018
Announcement Number: 
PA-15-058