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CTBR/CTSC Fall 2012 Colloqium: Natural Products: An Entry into Discovery Biology

Event Start Date: 
Friday, October 26, 2012 - 3:00pm
Event End Date: 
Friday, October 26, 2012 - 5:00pm

Jef K. DeBrabander, Ph.D.
Professor of Biochemistry
Julie and Louis Beecherl, Jr., Chair in Medical Science Department of Biochemistry
UT Southwestern Medical Center, Dallas, Texas

Supported by the National Institute on Minority Health and Health Disparities, National Institutes of Health – 8 G12 MD007599-27 (formerly NCRR Grant #G12 RR003037) and grant #2UL1TR000457-06 (formerly grant #UL1RR024996) of the CTSC at Weill Cornell Medical College.

Abstract: Natural products still represent an ideal platform to discover novel biological targets and pathways. They also remain a mainstay in the drug discovery process, in particular for oncological indications and infectious dIseases. Our group has targeted many complex natural products with novel architectures and potent biological activity. I will focus in this presentation on two natural products, namely salicylihalamide and psymberin. Our research program led to the discovery of the biological targets of these intriguing natural products, and the development of leads for the treatment of cancer and viral infections.

Video Presentation


Ida K. Lang Recital Center, Room 424 Hunter North
Hunter College
695 Park Avenue
(Enter on East 69th Street between Lexington and Park Avenues)

Contact person and information for event: 

Denise Charles, CTBR

dc674 (at) hunter (dot) cuny (dot) edu