CTBR/Biology Department Seminar: Non-Invasive Imaging of Cancer using 89Zr-radiolabeled Imaging Probes
Nerissa Therese Viola-Villegas, Ph.D.
Memorial Sloan-Kettering Cancer Center
Abstract: Over the past several decades, biomedical cancer research has made significant advances in achieving its goal: preemptive medicine via interrogation of tumor biology. At the very core of this vision is molecular imaging. This growing interdisciplinary field has invaluably supported the progression of survival rates and clinical management of malignant growth through guided detection of tumors at their early and recurrent stages at the molecular level. Molecular imaging through immuno-positron emission tomography (immunoPET) has proven to be a powerful tool to non-invasively screen and detect for cancer with remarkable specificity, providing the least patient burden. Here, in this study, strategies to delineate pancreatic and prostate malignancies through antibody-based imaging probes employing the positron emitting 89Zirconium (t1/2 ~3.78 d) will be presented. Ultimately, these burgeoning preclinical imaging technologies will be propelled toward clinical translation for better patient care.
Refreshments will be served at 11:45AM
Supported by NIH Funds from: CTBR
Room 926 North (69th Street between Park and Lexington)
dc674 (at) hunter (dot) cuny (dot) edu